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tar-nm-u23  (BioAutomation corporation)

 
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    Structured Review

    BioAutomation corporation tar-nm-u23
    a Overlay of conformers showing motions in bulge residues for linear (| β h | < 45°), intermediate bend (45° < | β h | < 70°) and kinked (| β h | > 70°) inter-helical conformations in the FARFAR-NMR and Anton-MD-NMR ensembles. b , c The fractional populations of conformers with the number of b extra-helical and c C2′- endo residues (color-coded) in the bulge residues <t>(U23,</t> C24, and U25) as a function of bending angle in the FARFAR-NMR (“F”) and Anton-MD-NMR (“A”) ensembles ( N = 20). d Comparison of one coaxially stacked FARFAR-NMR conformer with the crystal structure of Ca 2+ -bound <t>TAR</t> (PDBID: 397D) . e Nm shifts sugar-pucker equilibrium towards C3′- endo . f Overlay of 2D [ 13 C, 1 H] HSQC NMR spectra of the aromatic spins for TAR-Nm-C24 without Mg 2+ (blue) with blue arrows indicate unstacking, TAR without Mg 2+ (cyan) and TAR with 3 mM Mg 2+ (red) with red arrows indicating increased coaxial stacking.
    Tar Nm U23, supplied by BioAutomation corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/tar-nm-u23/pmc07608651-253-1-14?v=BioAutomation+corporation
    Average 90 stars, based on 1 article reviews
    tar-nm-u23 - by Bioz Stars, 2026-08
    90/100 stars

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    1) Product Images from "Rapid and accurate determination of atomistic RNA dynamic ensemble models using NMR and structure prediction"

    Article Title: Rapid and accurate determination of atomistic RNA dynamic ensemble models using NMR and structure prediction

    Journal: Nature Communications

    doi: 10.1038/s41467-020-19371-y

    a Overlay of conformers showing motions in bulge residues for linear (| β h | < 45°), intermediate bend (45° < | β h | < 70°) and kinked (| β h | > 70°) inter-helical conformations in the FARFAR-NMR and Anton-MD-NMR ensembles. b , c The fractional populations of conformers with the number of b extra-helical and c C2′- endo residues (color-coded) in the bulge residues (U23, C24, and U25) as a function of bending angle in the FARFAR-NMR (“F”) and Anton-MD-NMR (“A”) ensembles ( N = 20). d Comparison of one coaxially stacked FARFAR-NMR conformer with the crystal structure of Ca 2+ -bound TAR (PDBID: 397D) . e Nm shifts sugar-pucker equilibrium towards C3′- endo . f Overlay of 2D [ 13 C, 1 H] HSQC NMR spectra of the aromatic spins for TAR-Nm-C24 without Mg 2+ (blue) with blue arrows indicate unstacking, TAR without Mg 2+ (cyan) and TAR with 3 mM Mg 2+ (red) with red arrows indicating increased coaxial stacking.
    Figure Legend Snippet: a Overlay of conformers showing motions in bulge residues for linear (| β h | < 45°), intermediate bend (45° < | β h | < 70°) and kinked (| β h | > 70°) inter-helical conformations in the FARFAR-NMR and Anton-MD-NMR ensembles. b , c The fractional populations of conformers with the number of b extra-helical and c C2′- endo residues (color-coded) in the bulge residues (U23, C24, and U25) as a function of bending angle in the FARFAR-NMR (“F”) and Anton-MD-NMR (“A”) ensembles ( N = 20). d Comparison of one coaxially stacked FARFAR-NMR conformer with the crystal structure of Ca 2+ -bound TAR (PDBID: 397D) . e Nm shifts sugar-pucker equilibrium towards C3′- endo . f Overlay of 2D [ 13 C, 1 H] HSQC NMR spectra of the aromatic spins for TAR-Nm-C24 without Mg 2+ (blue) with blue arrows indicate unstacking, TAR without Mg 2+ (cyan) and TAR with 3 mM Mg 2+ (red) with red arrows indicating increased coaxial stacking.

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    tar-nm-u23  (BioAutomation corporation)
    90
    BioAutomation corporation tar-nm-u23
    a Overlay of conformers showing motions in bulge residues for linear (| β h | < 45°), intermediate bend (45° < | β h | < 70°) and kinked (| β h | > 70°) inter-helical conformations in the FARFAR-NMR and Anton-MD-NMR ensembles. b , c The fractional populations of conformers with the number of b extra-helical and c C2′- endo residues (color-coded) in the bulge residues <t>(U23,</t> C24, and U25) as a function of bending angle in the FARFAR-NMR (“F”) and Anton-MD-NMR (“A”) ensembles ( N = 20). d Comparison of one coaxially stacked FARFAR-NMR conformer with the crystal structure of Ca 2+ -bound <t>TAR</t> (PDBID: 397D) . e Nm shifts sugar-pucker equilibrium towards C3′- endo . f Overlay of 2D [ 13 C, 1 H] HSQC NMR spectra of the aromatic spins for TAR-Nm-C24 without Mg 2+ (blue) with blue arrows indicate unstacking, TAR without Mg 2+ (cyan) and TAR with 3 mM Mg 2+ (red) with red arrows indicating increased coaxial stacking.
    Tar Nm U23, supplied by BioAutomation corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/tar-nm-u23/pmc07608651-253-1-14?v=BioAutomation+corporation
    Average 90 stars, based on 1 article reviews
    tar-nm-u23 - by Bioz Stars, 2026-08
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    a Overlay of conformers showing motions in bulge residues for linear (| β h | < 45°), intermediate bend (45° < | β h | < 70°) and kinked (| β h | > 70°) inter-helical conformations in the FARFAR-NMR and Anton-MD-NMR ensembles. b , c The fractional populations of conformers with the number of b extra-helical and c C2′- endo residues (color-coded) in the bulge residues (U23, C24, and U25) as a function of bending angle in the FARFAR-NMR (“F”) and Anton-MD-NMR (“A”) ensembles ( N = 20). d Comparison of one coaxially stacked FARFAR-NMR conformer with the crystal structure of Ca 2+ -bound TAR (PDBID: 397D) . e Nm shifts sugar-pucker equilibrium towards C3′- endo . f Overlay of 2D [ 13 C, 1 H] HSQC NMR spectra of the aromatic spins for TAR-Nm-C24 without Mg 2+ (blue) with blue arrows indicate unstacking, TAR without Mg 2+ (cyan) and TAR with 3 mM Mg 2+ (red) with red arrows indicating increased coaxial stacking.

    Journal: Nature Communications

    Article Title: Rapid and accurate determination of atomistic RNA dynamic ensemble models using NMR and structure prediction

    doi: 10.1038/s41467-020-19371-y

    Figure Lengend Snippet: a Overlay of conformers showing motions in bulge residues for linear (| β h | < 45°), intermediate bend (45° < | β h | < 70°) and kinked (| β h | > 70°) inter-helical conformations in the FARFAR-NMR and Anton-MD-NMR ensembles. b , c The fractional populations of conformers with the number of b extra-helical and c C2′- endo residues (color-coded) in the bulge residues (U23, C24, and U25) as a function of bending angle in the FARFAR-NMR (“F”) and Anton-MD-NMR (“A”) ensembles ( N = 20). d Comparison of one coaxially stacked FARFAR-NMR conformer with the crystal structure of Ca 2+ -bound TAR (PDBID: 397D) . e Nm shifts sugar-pucker equilibrium towards C3′- endo . f Overlay of 2D [ 13 C, 1 H] HSQC NMR spectra of the aromatic spins for TAR-Nm-C24 without Mg 2+ (blue) with blue arrows indicate unstacking, TAR without Mg 2+ (cyan) and TAR with 3 mM Mg 2+ (red) with red arrows indicating increased coaxial stacking.

    Article Snippet: TAR, TAR-Nm-U23, and TAR-Nm-C24 RNA samples were synthesized using a MerMade 6 Oligo Synthesizer (BioAutomation) via solid-phase synthesis using standard phosphoramidite chemistry and deprotection protocols.

    Techniques: